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Trusopt is a prescription medication approved for the treatment of glaucoma and high eye pressure. It comes in the form of an eye drop and is generally applied three times a day. The medicine lowers pressure in the eye by decreasing the amount of fluid the eye produces. Common side effects can include eye burning, stinging, or discomfort.

What Is Trusopt?

Trusopt® (dorzolamide hydrochloride) is a prescription eye drop. It is approved to treat high eye pressure in people with chronic open-angle glaucoma or ocular hypertension.
(Click Trusopt Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Brand-name Trusopt is manufactured by Merck & Co., Inc. Generic versions are made by various manufacturers.

How Does Trusopt Work?

Trusopt belongs to a group of drugs called carbonic anhydrase inhibitors. Carbonic anhydrase is an enzyme found in many places throughout the body, including the eye. By inhibiting this enzyme, Trusopt lowers the eye pressure and decreases the amount of fluid the eye produces (known as aqueous humor).

When and How to Use It

General considerations to keep in mind during treatment with Trusopt include the following:
  • This medication comes in the form of an eye drop. It is used in the affected eye(s) three times a day.
  • Soft contact lenses can absorb the preservative (benzalkonium chloride) in these eye drops. In order to avoid this problem, you must remove the lenses before using Trusopt and wait at least 15 minutes before reinserting them.
  • If you use other eye drops in addition to Trusopt, wait at least 10 minutes between using Trusopt and the other eye medication.
  • In order to prevent contamination of the drops, do not touch the tip of the dropper to any surface, including the surface of the eye or the skin.
  • For Trusopt to work properly, it must be taken as directed.

Trusopt Eye Drop Information

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