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Travatan Warnings and Precautions

To help ensure safe treatment, talk to your healthcare provider if you have an inflammatory eye condition or any allergies before using Travatan. Warnings and precautions also include being aware of potential drug interactions and watching out for side effects, such as eye color changes or vision changes. Do not use Travatan if you are allergic to any components of the medicine.

What Should I Tell My Healthcare Provider Before Taking Travatan?

You should talk with your healthcare provider prior to taking Travatan® (travoprost ophthalmic solution) if you:
  • Have any allergies, including allergies to food, dyes, or preservatives
  • Have an inflammatory eye condition, such as iritis or uveitis
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding.
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
In April 2010, Alcon, Inc., announced that it would no longer be making regular Travatan. However, Travatan Z (which contains a gentler preservative) will continue to be available.

Specific Precautions and Warnings for Travatan

Warnings and precautions to be aware of prior to taking Travatan include the following:
  • Travatan can cause increased pigmentation (darkening) of certain tissues. It can cause a darkening of the iris (the colored part) of the eyes, the eyelids, and the eyelashes. While darkening of the eyelids and eyelashes usually improves after the medication is stopped, eye darkening is usually permanent. This is most noticeable in people with light-colored eyes (such as blue eyes), as Travatan tends to make the eyes more brown. These changes are not dangerous, and you can keep taking the medicine if they occur.
  • There have been reports of macular edema (swelling of the macula of the eye) in some people who took eyedrops similar to Travatan. Be sure to let your healthcare provider know if you have any vision changes during treatment, as they may be a sign of macular edema.
  • Travatan can also cause longer and thicker eyelashes, as well as eyelashes that grow in wrong directions.
  • There have been a few cases of bacterial keratitis (a dangerous infection of the cornea of the eye that can quickly lead to blindness) in people who use eyedrops. These cases were caused by accidental contamination of the bottle by the users, who usually already had some damage or disease of the cornea. It is very important to prevent contamination of the bottle. Never touch the tip of the bottle with your eye, hands, or any other surfaces.
  • Travatan is not approved for angle closure glaucoma, inflammatory glaucoma, or neovascular glaucoma, as it has not been thoroughly studied for these types.
  • Make sure your healthcare provider knows if you have a history of iritis or uveitis (certain inflammatory conditions of the eye). In general, Travatan should be avoided if you currently have eye inflammation.
  • If you develop any eye condition or require eye surgery, let your healthcare provider know. You may be advised to temporarily stop taking Travatan.
  • If you wear contact lenses, you must take them out before using Travatan and wait at least 15 minutes before reinserting them.
  • Wait at least five minutes in between using Travatan and any other eyedrops.
  • Travatan can potentially interact with a few other medications (see Travatan Drug Interactions).
  • Travatan is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not currently known (see Travatan and Pregnancy).
  • It is unknown whether the medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking Travatan (see Travatan and Breastfeeding).
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