Glaucoma Home > Rescula

A healthcare provider may prescribe Rescula to help lower eye pressure in people with open angle glaucoma. It is also licensed to lower eye pressure in those who have ocular hypertension. Rescula comes as a solution that is used in the eye twice daily. Although most people do not experience any problems with it, side effects are possible and may include burning, stinging, and dry eyes.

What Is Rescula?

Rescula® (unoprostone ophthalmic solution) is a prescription eye drop approved to lower eye pressure in people who have open angle glaucoma. It is also approved to lower eye pressure in people with ocular hypertension (high pressure in the eye).  
(Click Rescula Uses for more information, including possible off-label uses.)

Who Makes This Medication?

Rescula is made by Sucampo Pharma Americas, LLC.

Clinical Effects

Eye pressure is measured in millimeters of mercury (mmHg). In clinical studies, Rescula was shown to reduce eye pressure by 3 to 4 mmHg in people with an average eye pressure of 23 mmHg. An eye pressure over 22 mmHg is considered higher than normal.

How Does Rescula Work?

Medications used to lower eye pressure usually work by either decreasing the amount of fluid produced in the eye (known as the aqueous humor) or by increasing drainage of the aqueous humor from the eye. Rescula is thought to work by increasing fluid drainage from the eye.
More specifically, the drug may open certain channels in the trabecular network, a sponge-like tissue in the eye that is responsible for draining aqueous humor from the eye. However, the exact way in which Rescula works to reduce intraocular pressure is unknown.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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