The U.S. Food and Drug Administration has assigned an "AT" rating to all versions of generic Cosopt (dorzolamide/timolol), which means they are considered equivalent to the brand-name drug. Like brand-name Cosopt, the generic is applied to the affected eye(s) twice a day to treat high eye pressure.
Cosopt® (dorzolamide/timolol) is a prescription eye drop approved for the treatment of glaucoma and high eye pressure. It contains two different active ingredients: dorzolamide hydrochloride (which belongs to a group of medications known as carbonic anhydrase inhibitors) and timolol maleate (a beta blocker). Cosopt lowers eye pressure by decreasing the fluid production in the eye.
Brand-name Cosopt is manufactured by Merck & Co., Inc. However, the patent has expired, and a generic version is now available.
Like brand-name Cosopt, the generic versions come in only one strength, with 2% dorzolamide and 0.5% timolol. And like brand-name Cosopt, generic Cosopt is available only in 10-mL bottles. It is also available in a preservative-free version, in single-use containers. This version (Cosopt PF) is not yet available in generic form.
Generic Cosopt is made by various companies, such as:
- Apotex Corporation
- Bausch & Lomb, Inc.
- Falcon Pharmaceuticals, Ltd.
- Hi-Tech Pharmacal Co., Inc.
- Prasco Laboratories
- Sandoz, Inc.
All generic medications must undergo certain tests to compare them to brand-name medications. The U.S. Food and Drug Administration (FDA) then looks at these tests to decide if the generics are equivalent to the brand-name medications and assigns a rating to each one.
An "AT" rating means that the FDA has determined that a generic medication is equivalent to a brand-name medication. All of the generic Cosopt versions currently available have an "AT" rating, meaning they should be equivalent to Cosopt.
However, generic medications are allowed to have different inactive ingredients than the brand-name medication. This might include fillers, dyes, or other ingredients that may cause problems for people with allergies or sensitivities.