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Cosopt Warnings and Precautions

Cosopt could make certain medical conditions worse, such as congestive heart failure or myasthenia gravis. Precautions and warnings with Cosopt also apply to women who are pregnant or breastfeeding, people with a history of allergies, and people who have an upcoming surgery. In order to ensure your safety with this medication, tell your healthcare provider about any other drugs you are using and any other conditions you have.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Cosopt® (dorzolamide/timolol) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Cosopt

Warnings and precautions to be aware of prior to using Cosopt include the following:
  • Cosopt contains a sulfonamide ("sulfa" drug) and can cause serious reactions in people allergic to such medications.
  • Even though Cosopt is an eye drop, a significant amount of the medication may be absorbed into the bloodstream. Therefore, most of the usual warnings and precautions with other carbonic anhydrase inhibitors or beta blockers also apply to Cosopt.
  • This medication may worsen allergic reactions and may make epinephrine (one of the standard treatments for life-threatening allergic reactions) less effective. If you have a history of severe allergic reactions, this product may not be the best choice for you.
  • Like all beta blockers, Cosopt can worsen heart failure in some situations. If you have congestive heart failure, your healthcare provider may need to monitor you very closely while you take Cosopt. Let your healthcare provider know immediately if your heart failure symptoms seem to become worse.
  • Beta blockers can worsen breathing problems like asthma or COPD. In many cases, Cosopt is not recommended for people with such lung problems.
  • This medication may worsen myasthenia gravis symptoms or may even cause this condition. Let your healthcare provider know if you develop symptoms of this problem, such as muscle weakness, double vision, or a droopy eyelid.
  • If you will be having surgery, make sure your surgeon and anesthesiologist know you take Cosopt, as it may affect the choice of medications used during the surgery.
  • Beta blockers can mask some of the symptoms of low blood sugar (hypoglycemia), particularly the "racing heart" feeling. This can cause serious problems for people with diabetes, who need to be able to sense that they have low blood sugar in order to correct it before it becomes life-threatening. Some beta blockers may also worsen low blood sugar, although it is not known if this is a concern with Cosopt.
  • Beta blockers can mask some of the symptoms of an overactive thyroid (hyperthyroidism).
  • Cosopt can potentially interact with a number of other medications (see Cosopt Drug Interactions).
  • This product has not been adequately studied in people with liver or kidney problems. Cosopt is not recommended for people with severe kidney problems and should be used with caution in people with liver problems.
  • If you wear soft contact lenses, be sure to remove them before each Cosopt dosage and wait at least 15 minutes before reinserting them. Cosopt contains a preservative (benzalkonium chloride) that can bind to soft contact lenses.
  • If you will be having eye surgery or develop any other eye problems or conditions (such as an infection), check with your healthcare provider about whether you should continue to take this medication.
  • If you use other eye drops, be sure to separate your dose of Cosopt from that of the other drops by at least 10 minutes.
  • Cosopt is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not currently known (see Cosopt and Pregnancy).
  • At least one of the active ingredients in this product passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Cosopt and Breastfeeding).

Cosopt Eye Drops

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