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Cosopt Drug Interactions
from eMedTV.comMethacholine
It is dangerous to combine methacholine with Cosopt. Doing so could cause severe, asthma-like breathing problems that are not easily corrected. These drugs should never be combined.
Other Beta Blockers
Cosopt contains a beta blocker. Caution should be used if Cosopt is combined with other beta blockers, especially oral beta blockers (taken by mouth). Such combinations may increase the risk of side effects. In addition, two different beta blocker eye drops should not be taken at the same time.
Other Carbonic Anhydrase Inhibitors
Cosopt contains a carbonic anhydrase inhibitor. Even though it is an eye drop, some of the medication is absorbed into the rest of the body. Due to the possibility of increased side effects, Cosopt should not be combined with another carbonic anhydrase inhibitor.
Reserpine
Combining reserpine with a beta blocker can increase the risk of serious side effects. You may need to be monitored closely if you take these drugs together. In some cases, Cosopt should not be combined with reserpine.
Other Eye Medications
If you take other eye medications, be sure to separate your Cosopt dosage from that of the other medication(s) by at least 10 minutes.
Salicylates
There have been rare reports of serious drug interactions (resulting in serious problems) in people taking high-dose salicylates and oral carbonic anhydrase inhibitors together. The risk of such problems is probably extremely small for Cosopt, since it is given as an eye drop, especially if combined with low or normal doses of salicylates.
Final Thoughts
It is possible that not every Cosopt drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the interactions that may apply to you.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD