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Combigan and Breastfeeding

The full risks of breastfeeding while using Combigan (brimonidine/timolol) are currently unknown. The manufacturer advises women to avoid the eye drop while breastfeeding. Because the medication may enter the bloodstream, it could pass through breast milk and cause problems in a nursing infant. If your healthcare provider recommends using this eye drops while breastfeeding, watch for any side effects in your child.

Can Breastfeeding Women Use Combigan?

At least one of the active ingredients in Combigan® (brimonidine/timolol) passes through breast milk in humans. The manufacturer recommends that this medication be avoided in breastfeeding women. Therefore, if you are breastfeeding a child, you should talk with your healthcare provider before using Combigan.
 

Safety Issues Surrounding Combigan and Breastfeeding

No studies have been done to see if brimonidine (one of the active ingredients in Combigan) passes through breast milk in humans. It is known to pass through breast milk in animals, though.
 
The other ingredient in Combigan (timolol) does pass through breast milk, even if taken as an eye drop. Serious problems (such as a dangerously low heart rate or low blood pressure) could occur in the nursing infant. Therefore, if your healthcare provider decides that it is okay for you to take timolol while breastfeeding, your infant should be monitored to make sure that no problems occur.
 
In general, using timolol eye drops is considered to be much safer for use while breastfeeding than taking timolol tablets. Using the eye drops results in much lower amounts of the drug being passed through breast milk.
 
It is important to understand that even though Combigan is an eye drop, some of the medication could reach the bloodstream, which means it could pass through breast milk. With normal use of Combigan, it is unlikely that a large amount of the drug would reach the breast milk.
 
However, the possibility of problems cannot be entirely eliminated, since this medication has never been studied in breastfeeding women. If your healthcare provider recommends taking Combigan while breastfeeding, be sure to watch for any side effects in your child.
 
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