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Alphagan and Pregnancy

Animal studies on Alphagan (brimonidine) show that this drug is probably safe for use during pregnancy. Alphagan did not appear to cause any harm when large doses were give to pregnant rats. However, animals don't always respond to medications the same way that humans do, so make sure to talk to your healthcare provider about the risks and benefits of using Alphagan if you are expecting.

Can Pregnant Women Use Alphagan?

Alphagan® (brimonidine tartrate) is an eye medication approved for the treatment of high eye pressure and open-angle glaucoma. Based on the results of animal studies, Alphagan appears to be relatively safe for use during pregnancy, although the full risks to humans are currently unknown.
It is important to understand that even though Alphagan is an eye drop, some of the medication reaches the bloodstream and could, therefore, affect a developing fetus.

What Is Pregnancy Category B?

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans, but do not appear to cause harm to the fetus in animal studies.
Also, medications that have been shown to be safe for use in pregnancy in humans (but have caused problems in laboratory animals) are also given a Category B rating.
In research studies, giving very large doses of brimonidine (the active ingredient in Alphagan) by mouth to pregnant rats did not appear to cause any problems.
However, it is important to note that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category B medicine should be given to a pregnant woman only if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child.
Pregnancy and Pain

Alphagan Medication Information

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